United States of America v. Antoinen Dion Hampton and Reginald Tremayne Jackson

Little Rock, Arkansas, criminal defense lawyers represented the Defendants charged with dozens of pharmacy burglaries and stolen controlled substances worth millions of dollars.

On November 8, 2023, a federal grand jury indicted Antoinen Dion Hampton, AGE 39, and Reginald Tremayne Jackson, AGE 35,, along with 16 other defendants, and on July 2, 2024, the indictment was superseded to add an additional 24 defendants. On October 23, 2025, Hampton pleaded guilty to conspiracy to distribute oxycodone, hydrocodone, alprazolam, and other Schedule II, III, IV, and V controlled substances and conspiracy to commit money laundering. On September 4, 2025, Jackson pleaded guilty to conspiracy to distribute and possess with intent to distribute oxycodone, hydrocodone, alprazolam, and other Schedule II, III, IV, and V controlled substances.

An investigation revealed that Hampton and Jackson were involved in a drug trafficking organization that included documented gang members from the 5th Ward area in Houston, Texas. Investigators discovered more than 96,000 tablets of Schedule II controlled substances—including oxycodone, hydrocodone, Adderall, and others—were stolen were stolen from pharmacies throughout the United States, including pharmacies Arkansas, Oklahoma, Kansas, Georgia, and Florida. The street value of all controlled substances stolen by the organization in the Arkansas burglaries alone is close to $1.6 million. Investigators also seized six firearms, approximately $79,000 in U.S. currency, and custom jewelry retailing approximately $330,000. The quantity of Schedule II controlled substances stolen from pharmacies and distributed has a street value of more than $12,000,000.

Hampton’s criminal history includes several felony convictions for burglary with intent to commit theft, burglary of a building with intent to commit theft, and burglary of a dwelling structure. Hampton participated in over 50 burglaries in pharmacies across the United States, including in Arkansas, Georgia, Tennessee, South Carolina, Utah, Colorado, Florida, Idaho, Illinois, Indiana, Kansas, Kentucky, Louisiana, Michigan, North Carolina, Ohio, Virginia, and Wyoming.

Because Jackson has at least two prior convictions for a violent felony or serious drug offense, he is classified as a career offender. Jackson participated in 10 burglaries of pharmacies across Arkansas and Oklahoma. Jackson’s criminal history includes a September 20, 2023, federal conviction for burglary of a business premises registered with the Drug Enforcement Administration (DEA) and he was sentenced to 36 months in federal prison, three years’ supervised release, and ordered to pay $9,347.45 in restitution. Jackson has felony state convictions for second-degree robbery and aggravated robbery with a deadly weapon.

Judge Miller also sentenced Hampton and Jackson each to three years’ supervised release. Restitution will be ordered at a later date. There is no parole in the federal system.

On September 4, 2024, Keith Wayne Brown, 36, of Humble, Texas, who was the leader of the pharmacy burglary ring, pleaded guilty to conspiracy to distribute controlled substances and conspiracy to commit money laundering. On January 16, 2025, Judge Miller sentenced Brown to serve 209 months, over 17 years, in federal prison, three years’ supervised release, and ordered him to pay $272,937.42 in restitution.

On April 18, 2025, Judge Miller sentenced Alexis Simone Garner, 33, also from Houston, to serve one year and one day in federal prison for conspiracy to money launder. Judge Miller also sentenced Garner to three years’ supervised release and ordered her to pay $67,572.73 in restitution.

Investigators with the DEA, Little Rock District Office, worked in conjunction with the following law enforcement partners:

DEA New Orleans Division (Little Rock District Office, Fayetteville Resident Office, Shreveport Resident Office, Mobile Resident Office),

DEA Special Operations Division,

DEA Houston Division (Houston TDS Group, Galveston Resident Office),

DEA Omaha Division,

DEA Rocky Mountain Division (Salt Lake City District Office, Cheyenne Resident Office),

DEA Atlanta Division (Columbia District Office),

DEA Miami Division (Pensacola District Office),

Federal Bureau of Investigation (FBI) Little Rock Field Office,

FBI Cast Team,

U.S. Marshals Service,

Oklahoma Bureau of Narcotics,

Harris County Sheriff’s Office,

League City Police Department (Dickinson, Texas),

Houston (Texas) Police Department Northeast Division Crime Suppression Team,

Houston (Texas) Police Department CID, and

Arkansas State Police.

The case is being prosecuted in the Eastern District of Arkansas by Assistant United States Attorney Amanda Fields.

This prosecution is part of the Homeland Security Task Force (HSTF) initiative established by Executive Order 14159, Protecting the American People Against Invasion. The HSTF is a whole-of-government partnership dedicated to eliminating criminal cartels, foreign gangs, transnational criminal organizations, and human smuggling and trafficking rings operating in the United States and abroad. Through historic interagency collaboration, the HSTF directs the full might of United States law enforcement towards identifying, investigating, and prosecuting the full spectrum of crimes committed by these organizations, which have long fueled violence and instability within our borders. In performing this work, the HSTF places special emphasis on investigating and prosecuting those engaged in child trafficking or other crimes involving children. The HSTF further utilizes all available tools to prosecute and remove the most violent criminal aliens from the United States. HSTF Little Rock comprises agents and officers from state and local task force agencies with the prosecution being led by the United States Attorney’s Office for the Eastern District of Arkansas.

Hampton was sentenced to 188 months in prison and Jackson was sentenced to 120 months.